Dermatologic infections: Topical: Apply 3 to 4 times daily to affected area
There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.
There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.
(For additional information see "Gentamicin (topical): Pediatric drug information")
Dermatologic infections: Infants, Children, and Adolescents: Topical: Cream, Ointment: Apply 3 to 4 times/day to affected area (Bradley 2017)
There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.
There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.
Refer to adult dosing.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Cream, External:
Generic: 0.1% (15 g, 30 g)
Ointment, External:
Generic: 0.1% (15 g, 30 g)
Yes
For external use only; not for ophthalmic use. Apply gently to affected area; may cover with gauze dressing.
For external topical use only; not for ophthalmic use. Apply a small amount gently to the cleansed affected area; may cover with gauze dressing.
Dermatologic infections: Topical treatment of superficial dermatologic infections
Gentamicin may be confused with gentian violet, kanamycin, vancomycin
The following adverse drug reactions and incidences are derived from product labeling unless otherwise specified.
Frequency not defined.
Dermatologic: Erythema, pruritus
Hypersensitivity to gentamicin or any component of the formulation
Concerns related to adverse effects:
• Superinfection: Prolonged use may result in fungal or bacterial superinfection; discontinue if superinfection is noted.
• Sensitization: Topical use has been associated with local sensitization (redness, irritation); discontinue if sensitization is noted.
Other warnings/precautions:
• Long-term use: Not intended for long-term therapy.
None known.
There are no known significant interactions.
Interferes with bacterial protein synthesis by binding to 30S ribosomal subunit resulting in a defective bacterial cell membrane
Absorption: Systemic absorption is reported following topical application to burn patients (Sawchuk 1980).
Cream (Gentamicin Sulfate External)
0.1% (per gram): $1.00 - $3.29
Ointment (Gentamicin Sulfate External)
0.1% (per gram): $3.29
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