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Beano (alpha-galactosidase): Drug information

Beano (alpha-galactosidase): Drug information
(For additional information see "Beano (alpha-galactosidase): Patient drug information")

For abbreviations, symbols, and age group definitions used in Lexicomp (show table)
Brand Names: US
  • beano Meltaways [OTC];
  • beano [OTC]
Pharmacologic Category
  • Enzyme
Dosing: Adult

Intestinal gas/bloating: Oral: Note: Adjust dose according to the number of problem foods per meal. Doses of 300 to 1,200 galactosidase units have been shown to provide improvements in reducing symptoms of bloating and flatus (Di Stefano 2007)

Tablet, chewable (Beano): Usual dose: 2 to 3 tablets per meal

Tablet, orally disintegrating (Beano Meltaways): 1 tablet per meal

Dosing: Kidney Impairment: Adult

There are no dosage adjustments provided in the manufacturer’s labeling.

Dosing: Hepatic Impairment: Adult

There are no dosage adjustments provided in the manufacturer’s labeling.

Dosing: Pediatric

Intestinal gas/bloating: Children ≥12 years and Adolescents: Refer to adult dosing.

Dosing: Kidney Impairment: Pediatric

There are no dosage adjustments provided in the manufacturer’s labeling.

Dosing: Hepatic Impairment: Pediatric

There are no dosage adjustments provided in the manufacturer’s labeling.

Dosing: Older Adult

Refer to adult dosing.

Dosage Forms: US

Excipient information presented when available (limited, particularly for generics); consult specific product labeling.

Tablet, chewable, oral:

beano®: 150 Galactosidase units [scored]

Tablet, orally disintegrating, oral:

beano® Meltaways: 300 Galactosidase units [strawberry flavor]

Generic Equivalent Available: US

No

Administration: Adult

Must be administered just before or with first bite of food identified to cause flatus and/or bloating.

Chewable tablet (Beano): Swallow, chew, or crumble on food. Take before or with initial bite of food; do not cook.

Orally-disintegrating tablets (Beano Meltaways): Take before meals; place on tongue and allow to dissolve.

Administration: Pediatric

Oral: Must be administered just before or with first bite of food (up to 30 minutes after first bite) to be effective.

Chewable tablet (beano): Swallow or chew before or with initial bite of food. Do not cook into recipes; heating can inactivate the enzyme.

Orally-disintegrating tablets (beano Meltaways): Take before meals; place on tongue and allow to dissolve.

Use: Labeled Indications

Intestinal gas/bloating: Prevention of flatulence and bloating attributed to a variety of grains, cereals, nuts, and vegetables

Medication Safety Issues
Sound-alike/look-alike issues:

beano may be confused with B&O (belladonna and opium)

Adverse Reactions

There are no adverse reactions listed in the manufacturer's labeling.

Contraindications

Hypersensitivity to any component of the formulation

Warnings/Precautions

Disease-related concerns:

• Diabetes: Patients with diabetes mellitus should consult a healthcare provider prior to use; can produce 2-6 g of carbohydrates for every 100 g of food treated.

Special populations:

• Galactosemic patients: Patients who are galactosemic should consult their healthcare provider prior to use.

• Pregnancy: Patients who are pregnant or breast-feeding should consult a healthcare provider.

Other warnings/precautions:

• Heat exposure: Heat can inactivate; do not cook.

Dietary Considerations

Must be taken just before or with initial bite of food to be effective. Although made from safe, food-grade mold, there is no evidence that individuals with an allergy to penicillin or molds would have an allergy to beano®. Galactosemics should consult their healthcare provider.

Mechanism of Action

Natural food enzyme that breaks down complex sugars in gassy foods, making them more digestible and less gassy.

REFERENCES

  1. “Alpha-Galactosidase to Prevent Gas,” Med Lett Drugs Ther, 1993, 35(893):29-30. [PubMed 8383798]
  2. Beano Ultra 800 (alpha-galactosidase enzyme) [prescribing information]. Tarrytown, NJ: Prestige Brands Inc; received February 2020.
  3. Di Stefano M, Miceli E, Gotti S, Missanelli A, Mazzocchi S, Corazza GR. The effect of oral alpha-galactosidase on intestinal gas production and gas-related symptoms. Dig Dis Sci. 2007;52(1):78-83. [PubMed 17151807]
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