Allergic conjunctivitis: Ophthalmic: Instill 1 drop in affected eye up to 4 times daily
There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.
There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.
Allergic conjunctivitis: Children ≥3 years and Adolescents: Refer to adult dosing.
There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.
There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.
Refer to adult dosing.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Solution, Ophthalmic, as difumarate:
Emadine: 0.05% (5 mL [DSC]) [contains benzalkonium chloride]
No
Ophthalmic: For topical ophthalmic use only, not for injection. Wash hands before use. To avoid contamination, do not touch dropper tip to eyelids or other surfaces when placing drops in eyes. Remove contact lenses prior to administration. Wait ≥10 minutes before reinserting lenses. Do not wear contact lenses if eyes are red.
Ophthalmic: For topical ophthalmic use only, not for injection. Wash hands before use. Remove contact lenses prior to administration. Wait ≥10 minutes following emedastine instillation before reinserting lenses. Do not wear contact lenses if eyes are red. To avoid contamination, do not touch dropper tip to eyelids or other surfaces when placing drops in eyes.
Allergic conjunctivitis: For the temporary relief of the signs and symptoms of allergic conjunctivitis
The following adverse drug reactions and incidences are derived from product labeling unless otherwise specified.
Frequency not always defined.
>10%: Central nervous system: Headache (11%)
1% to 10%:
Cardiovascular: Hyperemia
Central nervous system: Abnormal dreams
Dermatologic: Dermatitis, pruritus
Gastrointestinal: Dysgeusia
Neuromuscular & skeletal: Weakness
Ophthalmic: Blurred vision, corneal infiltrates, corneal staining, keratitis, lacrimation, transient burning or stinging in the eyes, xerophthalmia
Respiratory: Rhinitis, sinusitis
Hypersensitivity to emedastine or any component of the formulation
Special populations:
• Contact lens wearers: Contains benzalkonium chloride which may be absorbed by soft contact lenses; remove contact lenses prior to use and wait ≥10 minutes before reinserting.
Other warnings/precautions:
• Appropriate use: For topical ophthalmic use only. Do not wear contact lens if eye is red; not for the treatment of contact lens irritation. To avoid contamination, do not touch dropper tip to eyelids or other surfaces when placing drops in eyes.
None known.
There are no known significant interactions.
Adverse events have not been observed in animal reproduction studies. Systemic absorption is limited following ocular administration. Use during pregnancy is not expected to result in significant exposure to the fetus.
It is not known if emedastine is excreted in breast milk. The manufacturer recommends that caution be exercised when administering emedastine to nursing women.
Selective histamine H1-receptor antagonist for topical ophthalmic use
Absorption: Ocular: Minimal
Half-life elimination: Oral: Plasma: 3 to 4 hours
Solution (Emadine Ophthalmic)
0.05% (per mL): $31.84
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