Hemostasis: Topical: Apply evenly to wound
No dosage adjustment provided in manufacturer’s labeling.
No dosage adjustment provided in manufacturer’s labeling.
Refer to adult dosing.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Solution, External:
Astringyn: 259 mg/g (8 g) [contains benzalkonium chloride]
Monsels Ferric Subsulfate: (8 mL, 60 mL)
Yes
Topical: For external use only. Apply to wound using cotton applicator/swab. Avoid contact with eyes.
Hemostatic in minor surgical procedures
The following adverse drug reactions and incidences are derived from product labeling unless otherwise specified. Frequency not defined.
Dermatologic: Skin hyperpigmentation (application site)
There are no contraindications in the manufacturer’s labeling.
Concerns related to adverse effects:
• Hyperpigmentation: May cause heavy pigmentation at application sites, which may result in histologic artifacts (upon rebiopsy) or in radiographic artifacts.
Other warnings/precautions:
• Appropriate use: For external use only. If inadvertent ocular administration occurs wash eye(s) immediately with large amounts of water or normal saline for approximately 15 to 20 minutes or until no evidence of solution remains.
None known.
There are no known significant interactions.
Ferric subsulfate is used as a hemostatic agent following cervical biopsies (Manca 1997; Tam 2005). May cause vaginal pain if leakage of solution occurs (Tam 2005). A case report also describes use following a miscarriage; fertility was not impaired and a successful pregnancy occurred 7 months later (Disu 2007).
Hemostasis at site of application.
Causes agglutination of surface proteins resulting in hemostasis
Onset: Hemostasis: ≤20 seconds
Solution (Astringyn External)
259 mg/g (per gram): $1.14
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