Muscle/Joint pain: Topical: Apply a liberal amount to affected area as needed up to 4 times daily.
There are no dosage adjustments provided in the manufacturer's labeling.
There are no dosage adjustments provided in the manufacturer's labeling.
Children ≥12 years: Refer to adult dosing.
Refer to adult dosing.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Cream, External, as salicylate:
Arthricream: 10% (90 g)
Asper-Flex: 10% (85 g [DSC]) [aspirin free, menthol free, odorless; contains cetyl alcohol, methylparaben, propylparaben, trolamine (triethanolamine)]
Mobisyl: 10% (100 g, 226.8 g) [odorless; contains cetyl alcohol, edetate (edta) sodium (tetrasodium), methylparaben, propylene glycol, propylparaben, trolamine (triethanolamine)]
Myoflex: 10% (57 g, 113 g)
Myoflex: 10% (113 g [DSC]) [odorless; contains cetyl alcohol, methylparaben, propylparaben, trolamine (triethanolamine)]
Generic: 10% (85 g [DSC])
Lotion, External, as salicylate:
Penetran: (113 g [DSC]) [aspirin free, menthol free; contains brilliant blue fcf (fd&c blue #1), fd&c yellow #10 (quinoline yellow), methylparaben, polysorbate 80]
Penetran Plus: 2.5% (75 mL [DSC]) [aspirin free, capsaicin free, menthol free, salicylate free]
Tru-micin: 10% (100 mL [DSC]) [odorless; contains cetyl alcohol]
Ultracin T: 10% (120 mL) [paraben free; contains benzoic acid, cetearyl alcohol, propylene glycol]
Yes
Topical: Avoid contact with eyes and mucous membranes; do not apply to wounds, damaged skin, broken skin, or irritated skin. Massage into painful area until thoroughly absorbed. Do not bandage tightly or apply local heat (eg, heating pad) to the area being treated.
Topical: For external use only; avoid contact with eyes and mucous membranes. Do not apply to wounds or damaged skin. Do not bandage tightly or use with a heating pad.
Muscle/Joint pain: Temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backache, bruises, cramps, muscle strains, and sprains.
Myoflex may be confused with Mycelex
Biafine: Brand name for trolamine [multiple international markets], but also the brand name for a topical emulsion [U.S.]
The following adverse drug reactions and incidences are derived from product labeling unless otherwise specified.
1% to 10%:
Central nervous system: Confusion, drowsiness
Gastrointestinal: Diarrhea, nausea, vomiting
Respiratory: Hyperventilation
Other warnings/precautions:
• Self-medication (OTC use): Do not use on wounds, damaged skin, broken skin, or irritated skin. Stop use and call health care provider if irritation occurs or if conditions worsen, persist >7 days, or clears up then worsens again in a few days.
None known.
Warfarin: Salicylates (Topical) may enhance the anticoagulant effect of Warfarin. Risk C: Monitor therapy
Systemic absorption of salicylate occurs following topical administration of trolamine (Rabinowitz, 1984).
Cream (Mobisyl External)
10% (per gram): $0.06
Cream (Myoflex External)
10% (per gram): $0.07
Lotion (Ultracin T External)
10% (per mL): $3.65
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