Bicarbonate precursor: IV: Dosage depends on degree of acidosis
Refer to adult dosing.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Solution, Intravenous:
Generic: 5 mEq/mL (10 mL [DSC])
Yes
IV: Must be diluted prior to IV administration
Source of bicarbonate for prevention and treatment of mild-to-moderate metabolic acidosis
There are no adverse reactions listed in the manufacturer's labeling.
Hypernatremia, fluid retention, treatment of lactic acidosis
None known.
Alpha-/Beta-Agonists (Indirect-Acting): Alkalinizing Agents may increase the serum concentration of Alpha-/Beta-Agonists (Indirect-Acting). Risk C: Monitor therapy
Amantadine: Alkalinizing Agents may increase the serum concentration of Amantadine. Risk C: Monitor therapy
Amphetamines: Alkalinizing Agents may decrease the excretion of Amphetamines. Management: Consider alternatives to using amphetamines and alkalinizing agents in combination. If these agents must be used together, patients should be monitored closely for excessive amphetamine effects. Risk D: Consider therapy modification
Flecainide: Sodium Lactate may decrease the excretion of Flecainide. Risk C: Monitor therapy
Mecamylamine: Alkalinizing Agents may increase the serum concentration of Mecamylamine. Risk C: Monitor therapy
Memantine: Alkalinizing Agents may increase the serum concentration of Memantine. Risk C: Monitor therapy
QuiNINE: Alkalinizing Agents may increase the serum concentration of QuiNINE. Risk C: Monitor therapy
Animal reproduction studies have not been conducted.
The manufacturer recommends that caution be exercised when administering sodium lactate to nursing women.
Some products may contain sodium.
Solution (Sodium Lactate Intravenous)
5 mEq/mL (per mL): $0.30
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